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目的:探讨了直肠癌患者手术治疗前后血清CA50、CA242和Hcy水平的变化及意义。方法:应用放射免疫分析和免疫化学法对31例直肠癌患者进行了治疗前后血清CA50、CA242和Hcy检测,并与35名正常健康人作比较。结果:直肠癌患者在手术治疗前血清CA50、CA242和Hcy水平均非常显著地高于正常人组(P<0.01),直肠癌患者术后6个月则与正常人组比较无显著性差异(P>0.05)。结论:检测直肠癌患者血清CA50、CA242和Hcy水平的变化可有助于对病情的严重程度、病情的发展作出判断。
Objective: To investigate the changes and significance of serum CA50, CA242 and Hcy levels in patients with rectal cancer before and after surgical treatment. METHODS: Serum CA50, CA242 and Hcy levels were measured in 31 patients with rectal cancer before and after treatment using radioimmunoassay and immunochemistry, and compared with 35 normal healthy subjects. Results: The serum CA50, CA242, and Hcy levels in patients with rectal cancer were significantly higher than those in the normal group before surgery (P<0.01). There was no significant difference in the rectal cancer patients at 6 months after operation (P<0.01). P>0.05). Conclusion: Detecting the changes of serum CA50, CA242 and Hcy levels in patients with rectal cancer can help determine the severity of the disease and the development of the disease.