在动物实验和临床实践中均证明多巴胺有增加肾脏灌注的作用,已广泛地应用于休克伴少尿的病例中。然而,多巴胺只有通过静脉滴注及在滴注期间有效,因此能口服而起作用的多巴胺类药物在临床实践中价值最大。一种新的口服药Ibopamine(SB7505)是N-甲基多巴胺的二异丁酯与静脉滴注的多巴胺有类似的药理特征,心功能得到改善,肾血流增加使水和电解质的排泄增加。此药还能增加正常人和肾功能损害患者 In animal experiments and clinical practice have proved that dopamine increased renal perfusion has been widely used in shock cases with oliguria. However, dopamine is only effective by intravenous drip and during instillation, so dopamine, which acts orally, is most valuable in clinical practice. Ibopamine (SB7505), a new oral drug, has similar pharmacological properties as intravenous drip dopamine and improves cardiac function. Increased renal blood flow increases excretion of water and electrolytes. This medicine can also increase the normal and renal dysfunction patients