目的探讨小儿继发性低颅压的病因及临床特点。方法回顾分析20例小儿继发性低颅压综合征的临床资料。结果小儿低颅压综合征以体位性头痛及呕吐为主要表现,甘露醇的不当应用、腰穿、感染、脱水等为主要继发因素,经补液等治疗均痊愈。结论小儿继发性低颅压综合征预后良好,提高对本病的认识,避免医源性因素是防治关键。 Objective To investigate the etiology and clinical features of secondary intracranial hypotension in children. Methods A retrospective analysis of 20 cases of pediatric secondary intracranial pressure syndrome clinical data. Results Low intracranial pressure syndrome in children with postural headache and vomiting as the main performance, improper use of mannitol, lumbar puncture, infection, dehydration as the main secondary factors, such as rehydration therapy were cured. Conclusions The prognosis of children with secondary intracranial hypertension syndrome is good, and raising awareness of the disease and avoiding iatrogenic factors are the key to prevention and treatment.