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目的分析局部晚期胃癌患者施行联合尾侧半胰、脾脏切除术的疗效。方法总结1986年2月至2001年3月间对32例局部晚期胃癌患者施行联合尾侧半胰、脾脏切除术的疗效(观察组),并与同期施行姑息切除手术的15例胃癌患者(对照组)进行对照分析。结果观察组与对照组患者术后中位生存期分别为(25±3)个月和(19±5)个月。1年生存率分别为81.3%和73.3%(P>0.05),差异无统计学意义。3年存活率分别为34.4%和6.7%(P<0.05),差异具有统计学意义。结论只要掌握好手术适应证,对局部晚期胃癌患者施行联合尾侧半胰、脾脏切除术是安全、有效的。
Objective To analyze the curative effect of combined posterior pancreas and splenectomy in patients with locally advanced gastric cancer. Methods From February 1986 to March 2001, 32 patients with locally advanced gastric cancer underwent combined caudal pancreatectomy and splenectomy (observation group), and compared with 15 gastric cancer patients undergoing palliative resection (control group Group) for comparative analysis. Results The median postoperative survival time in observation group and control group was (25 ± 3) months and (19 ± 5) months respectively. The 1-year survival rates were 81.3% and 73.3% respectively (P> 0.05), with no significant difference. The 3-year survival rates were 34.4% and 6.7% respectively (P <0.05), the difference was statistically significant. Conclusion As long as the indications for surgery are well indicted, it is safe and effective to perform combined caudal pancreas and splenectomy in patients with locally advanced gastric cancer.