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姐妹染色单体互换（ＳＣＥ）检测是细胞遗传学研究领域的一项重要技术。临床上应用此技术主要是检测各种疾病患者骨髓和外周血淋巴细胞姐妹染色体互换频率；了解患者的ＤＮＡ损伤情况；检测各种物理治疗方法对细胞遗传影响及对药物的诱变性和致癌性进行研究。
Sister chromatid exchange (SCE) testing is an important technique in the field of cytogenetics. Clinical application of this technology is mainly to detect bone marrow and peripheral blood lymphocyte sister chromosomal exchange frequency of various diseases; to understand the patient’s DNA damage; detection of various physical therapies for cytogenetic and drug-induced mutagenicity and carcinogenicity Sex research.