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加兰他敏具有抗胆碱酯酶的作用,临床证实治疗小儿麻痹后遗症有很好的疗效。我们从国产石蒜中分得加兰他敏,经本所唐希灿等药理实验及临床试用结果,都与文献相符合。并于1964年通过国家鉴定。由上海南昌制药厂等进行生产。本文将简要报道有关生产的几个问题:高含量植物资源、采集季节与含量关系,以及合适的生产工艺。分述如下:一、加兰他敏高含量植物的寻找及采集季节与含量关系将从不同地区采集的7种石蒜和3种水仙的鳞茎,分别切碎晒干,磨成粗粉。按下流程分别提取和分离:
Galanthamine has anti-cholinesterase effect, clinically proven to have a good effect in the treatment of polio sequelae. We obtained galantamine from home-made Lycoris, and the results of pharmacological experiments and clinical trials by the Institute of Medicine Tang Xican were consistent with the literature. And in 1964 passed the national identification. It is produced by Shanghai Nanchang Pharmaceutical Factory. This article will briefly report on several issues related to production: high content of plant resources, collection of seasonal and content relationships, and appropriate production processes. Divide as follows: First, the search and collection of high-content Galanthamine plants Season and content relationship The bulbs of 7 species of Lycoris and 3 daffodils collected from different regions were chopped, dried, and ground into coarse powder. Press the process to extract and separate: