目的　探讨十二年来住院精神病人药源性迟发性运动障碍患病率变化特点及其影响因素。方法　应用AIMS对 1998年 4月 ,1993年 7月和 2 0 0 0年 12月正在住院病人进行评定 ,可疑者肌注海饿辛 ,并收集有关情况。结果　 1988年TD患者率为 13 .5 % ,1993年为 5 .5 % ,2 0 0 0年为 8.1%。 1993年TD患病率显著低于 1988年 ,TD患病率的高低与应用抗精神病药物品种及剂量有关联。结论　不同年代TD患病率也不同 ,并且与应用抗精神病药物及剂量有关 Objective To investigate the characteristics and influencing factors of the prevalence of drug-induced tardive dyskinesia in inpatients in the past 12 years. Methods AIMS was used to assess inpatients in April 1998, July 1993 and December 2000. Suspicious individuals were injected with sea-hungry and collected the relevant information. Results The prevalence of TD was 13.5% in 1988, 5.5% in 1993 and 8.1% in 2000. The prevalence of TD was significantly lower in 1993 than in 1988, and the prevalence of TD was correlated with the use of antipsychotic drugs and doses. Conclusion The prevalence of TD in different years is also different, and with the application of antipsychotic drugs and dose