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目的：观察鱼油和豆油对饲低硒及补硒粮喂养大鼠血谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）及血浆酶活力的影响。方法：ＧＳＨ－Ｐｘ采用ＤＴＮＢ法而血浆酶采用自动生化分析仪测定。结果：补加鱼油和豆油（５０ｇ／ｋｇ）饲料喂养大鼠４周，血中ＧＳＨ－Ｐｘ活力均明显降低；豆油组血浆中ＡＬＰ显著增加，ＧＯＴ、ＧＰＴ、α－ＨＢＤＨ有升高趋势；鱼油组ＧＰＴ显著增加。补硒后ＧＳＨ－Ｐｘ活力均显著升高，豆油中血浆酶活性有不同程度改善，鱼油组变化不显著。结论：多不饱和脂肪酸负荷能够降低动物体内抗氧化能力。鱼油（ω－３）、豆油（ω－６）对血浆酶的影响存在明显差异
Objective: To observe the effects of fish oil and soybean oil on glutathione peroxidase (GSH-Px) and plasma enzyme activities in feed rats fed with low selenium and selenium-enriched grains. Methods: GSH-Px using DTNB method and plasma enzyme using automatic biochemical analyzer. Results: The GSH-Px activity in blood was significantly decreased in fish fed with fish oil and soybean oil (50g / kg) for 4 weeks. The plasma ALP level increased significantly and the levels of GOT, GPT and α-HBDH increased. Group GPT increased significantly. GSH-Px vitality after selenium supplementation were significantly increased, plasma enzyme activity in soybean oil to varying degrees improved, the fish oil group did not change significantly. Conclusion: Polyunsaturated fatty acid load can reduce the antioxidant capacity in animals. Fish oil (omega-3), soybean oil (omega-6) on plasma enzymes there are significant differences