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抗病毒治疗是慢性乙型肝炎治疗的关键所在,但HBV宿主范围狭窄,缺少体外病毒繁殖系统。HBV转染细胞系2.2.15细胞株的建立为抗HBV药物的筛选提供了一个细胞模型,本文就2.2.15细胞株近十年来抗HBV中草药筛选情况作一综述。
Antiviral therapy is the key to the treatment of chronic hepatitis B, but the HBV host range is narrow and there is no in vitro viral propagation system. The establishment of a cell line of HBV transfected cell line 2.2.15 provides a cell model for the screening of anti-HBV drugs. This article reviewed the screening of anti-HBV herbal medicines in the 2.2.15 cell line for the past ten years.