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组织型纤溶酶原活化因子(tPA)是一种丝氨酸蛋白酶,是动物组织中的一种正常成分,是动物机体血凝系统的重要成员.它参与体内凝血与溶栓平衡的调控.但恶变的细胞也能合成并分泌tPA.
Tissue plasminogen activator (tPA) is a serine protease that is a normal component in animal tissues and an important member of the animal’s blood coagulation system. It is involved in the regulation of coagulation and thrombolysis in vivo. The cells also synthesize and secrete tPA.