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目的探讨不同治疗方案对急性心力衰竭患者的治疗价值。方法收集冠心病急性心力衰竭患者,随机分为:研究组和对照组,两组基础用药相同,研究组加用美托洛尔和曲美他嗪及加味真武汤。对比(1)两组治疗前后血压。(2)两组治疗前后24 h尿量、BNP及Lee氏心衰积分。(3)两组治疗前后急性心力衰竭中医症候积分。结果 (1)两组治疗前血压、24 h尿量、BNP、Lee氏心衰积分及急性心力衰竭中医症候积分比较无统计学意义(P>0.05);两组治疗后血压、24 h尿量、BNP、Lee氏心衰积分及急性心力衰竭中医症候积分比较有统计学意义(P<0.05)。结论冠心病伴急性心力衰竭发病率在人群中很高,在急性心力衰竭常规治疗方案中加入美托洛尔及曲美他嗪和加味真武汤,能改善患者症状,延缓心功能的恶化,提高生活质量。
Objective To investigate the therapeutic value of different treatment regimens in patients with acute heart failure. Methods Acute heart failure patients with coronary heart disease were collected and randomly divided into study group and control group. The two groups were given the same basic drugs. Metoprolol, trimetazidine and modified Zhenwu Decoction were used in the study group. Comparison (1) before and after treatment of blood pressure. (2) 24 h urine volume, BNP and Lee’s heart failure scores before and after treatment. (3) TCM symptom scores of acute heart failure before and after treatment in both groups. Results (1) Before treatment, blood pressure, 24-hour urine output, BNP, Lee’s heart failure scores and TCM symptom scores of acute heart failure were not statistically significant (P> 0.05) , BNP, Lee’s heart failure score and TCM symptom scores of acute heart failure were statistically significant (P <0.05). Conclusions The incidence of coronary heart disease with acute heart failure is high in the population. Adding metoprolol, trimetazidine and modified Zhenwu Tang to the routine treatment of acute heart failure can improve symptoms and delay the worsening of cardiac function and increase Quality of Life.