恶性胸腔积液(MPE)是恶性肿瘤通过直接或间接侵犯胸膜或胸膜原发性肿瘤所致。患者以MPE为首发症状或恶性肿瘤进展并发胸腔积液,往往提示病情已处于晚期,生存期仅4个月左右。大量胸腔积液可导致压迫性肺不张、限制性通气障碍、甚至呼吸衰竭,严重影响患者的呼吸循环功能,威胁患者生命。因此,采取积极有效的治疗措施以缓解患者症状、提高患者生存质量,显得尤为重要。 Malignant pleural effusion (MPE) is a malignancy caused by direct or indirect invasion of pleural or pleural primary tumors. Patients with MPE as the first symptom or malignant tumor complicated with pleural effusion, often prompted that the disease is already in its late stage of survival of only about 4 months. Large pleural effusion can lead to pressure atelectasis, restrictive ventilation disorders, and even respiratory failure, seriously affecting the patient’s respiratory cycle function, threatening the lives of patients. Therefore, to take active and effective treatment to alleviate the symptoms of patients, improve patient quality of life, it is particularly important.