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β_2微球蛋白(简称β_2m)是人体有核细胞产生的一种低分子蛋白(分子量11,800)。在体内产生量恒定,并易于从肾小球滤过,滤液中的β_2m 99.9％由近端肾小管吸收并分解,不再返流入血。若肾小球滤过率(GFR)下降,则血清β_2m水平增高。本院对正常足月新生儿和产时窒息新生儿进行血清β_2m放射免疫分析,研究新生儿窒息对肾功能的影响,现将结果报告如下。对象和方法一、检测对象 1.正常新生儿组:孕38～42周、体重≥2500g、无宫内窘迫,生后1分钟Apgar评分10,查体无异常发现的新生儿,共计54例。其中,男27例、女27例。
β_2 microglobulin (referred to as β_2m) is a low molecular weight protein (molecular weight 11,800) produced by human nucleated cells. Produced in the body constant, and easy from the glomerular filtration, the filtrate of β_2m99.9% by the proximal tubule absorption and decomposition, no return to the bloodstream. If the glomerular filtration rate (GFR) decreased, the serum β_2m levels increased. The hospital for normal full-term neonatal and neonatal aspartate asphyxia serum β_2m radioimmunoassay study of neonatal asphyxia on renal function, the results are reported as follows. Subjects and methods First, the test object 1 normal neonatal group: 38 to 42 weeks of pregnancy, body weight ≥ 2500g, no intrauterine distress, 1 minute Apgar score after birth, no abnormalities were found in the examination of newborns, a total of 54 cases. Among them, 27 males and 27 females.