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几个世纪以来,神经病变和脑病一直被视为严重接触重金属的结果。化学革命到来后,发现许多合成化学物质也具有神经毒性,如丙烯酰胺、二硫化碳、二甲胺丙腈、氯得康、正己烷、甲基正丁酮、有机磷如对硫磷、对溴磷、三邻磷酸苯甲酚、苯乙烯和2、4-二氯苯氧基醋酸。
For centuries, neuropathy and encephalopathy have been considered as a result of serious exposure to heavy metals. After the arrival of the chemical revolution, many synthetic chemicals were also found to be neurotoxic, such as acrylamide, carbon disulfide, dimethylamine propionitrile, chlordecone, n-hexane, methyl n-butanone, organic phosphorus such as parathion, , Tricresyl orthophosphate, styrene and 2,4-dichlorophenoxyacetic acid.