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本文阐述有关多中心试验的优越性及可能存在的问题,并介绍一个国外较典型的特大多中心试验的结构模式。对多中心试验的数据处理列出最常用的t检验、χ2检验及Ridit分析。
This article describes the advantages and possible problems with multicenter trials and presents a structural model of a particularly large multicentre trial abroad. The most commonly used t-test, χ2 test and Ridit analysis are listed for data processing in multicenter trials.