论文部分内容阅读
目的:了解p63、Calponin和Caldesmon三种新的肌上皮细胞标记物在涎腺肿瘤中的表达。方法:免疫组织化学S P法检测3 1例涎腺肿瘤(涎腺多形性腺瘤、肌上皮瘤、肌上皮癌、腺样囊性癌和上皮 肌上皮癌)中p63、Calponin和Caldesmon的表达。结果:p63、Calponin和Caldesmon均表达肿瘤中的肌上皮细胞。p63、Calponin和Caldesmon在3 1例涎腺肿瘤中的阳性率分别是93 .6%、77.4%和9.6%。结论:p63、Calponin是涎腺肿瘤中较好的肌上皮细胞标记物,与S 10 0、actin等传统标记物联合应用,更有助于涎腺肿瘤性肌上皮的鉴别诊断。
Objective: To investigate the expression of three new myoepithelial cell markers p63, Calponin and Caldesmon in salivary gland tumors. Methods: The expressions of p63, Calponin and Caldesmon in 31 salivary gland tumors (salivary gland pleomorphic adenoma, myoepithelioma, myoepithelial carcinoma, adenoid cystic carcinoma and epithelial myoepithelial carcinoma) were detected by immunohistochemical SP method. RESULTS: Both p63, Calponin and Caldesmon express myoepithelial cells in tumors. The positive rates of p63, Calponin and Caldesmon in salivary gland tumors were 93.6%, 77.4% and 9.6% respectively. Conclusion: p63, Calponin is a good myoepithelial cell marker in salivary gland tumors, which is more useful for the differential diagnosis of salivary gland tumorous myoepithelial cells in combination with traditional markers such as S 10 0 and actin.