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目的:对肾炎康联合依那普利治疗老年糖尿病肾病(DN)的疗效进行分析探讨。方法:将我院2013年月~2016年12月收治的182例老年DN患者随机分为对照组与观察组,对照组91例患者采用依那普利治疗,观察组91例患者采用依那普利联合肾炎康治疗,对比两组患者的治疗效果。结果:两组患者治疗后24h尿蛋白、BUN、Cr、TRF、MALB、β2MG、alMG、URBP均得到明显改善(P<0.05),且观察组明显优于对照组(P<0.05),观察组治疗有效率为91.21%,明显高于对照组的76.92%(P<0.05)。结论:对老年糖尿病肾病采用肾炎康联合依那普利治疗能够有效改善患者肾功能,减轻炎症反应,提高治疗效果,值得临床推广应用。
Objective: To investigate the therapeutic effect of nephritis combined with enalapril on senile diabetic nephropathy (DN). Methods: A total of 182 elderly DN patients admitted from January 2013 to December 2016 in our hospital were randomly divided into control group and observation group. 91 patients in control group were treated with enalapril. 91 patients in observation group were treated with enalapril Lee joint nephritis treatment, the treatment of patients in two groups compared. Results: The levels of urinary protein, BUN, Cr, TRF, MALB, β2MG, alMG and URBP in both groups were significantly improved after treatment (P <0.05), and the observation group was significantly better than the control group The effective rate of treatment was 91.21%, which was significantly higher than that of the control group (76.92%, P <0.05). Conclusion: The treatment of senile diabetic nephropathy with nephritis combined with enalapril can effectively improve renal function, reduce inflammation and improve the therapeutic effect, which is worthy of clinical application.