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目的进行炎琥宁与更昔洛韦治疗轻症手足口病的疗效对比,寻求门诊治疗手足口病安全有效的方案。方法将门诊600例轻症手足口病患儿随机分为治疗组300例和对照组300例,分别静脉给予炎琥宁5～10mg/(kg·d)和更昔洛韦5.0～7.5mg/(kg.d),疗程5d,对临床体征的变化进行分析。结果治疗组临床症状及体征均较对照组消失早(P<0.05),治疗组总有效率95.0%,对照组总有效率88.0%(P<0.05)。结论炎琥宁注射液治疗小儿手足口病疗程短、见效快、无明显不良作用。
Objective To compare the curative effect between Yanhu-ning and Ganciclovir for the treatment of mild hand-foot-mouth disease and seek out a safe and effective program for outpatient treatment of hand-foot-mouth disease. Methods A total of 600 outpatients with mild hand-foot-mouth disease were randomly divided into treatment group (300 cases) and control group (300 cases). Patients were given Yan Huoning 5 ~ 10 mg / (kg · d) and Ganciclovir 5.0 ~ 7.5 mg / (kg.d), treatment 5d, analysis of changes in clinical signs. Results The clinical symptoms and signs disappeared in the treatment group as compared with the control group (P <0.05). The total effective rate was 95.0% in the treatment group and 88.0% in the control group (P <0.05). Conclusion Yanhuning injection in children with HFMD treatment short, quick, no significant adverse effects.