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目的探讨早期实施血液滤过治疗对心肺复苏后患者的治疗作用。方法 42例心肺复苏成功的患者随机分为二组,对照组18例给予循环、呼吸支持、脑保护以及防治感染等治疗措施;观察组24例在上述常规治疗基础上,早期实施血液滤过治疗:心肺复苏成功后4h内开始行连续性静脉-静脉血液滤过(CVVH)治疗12h,观察二组多器官功能衰竭综合征(MODS)严重度评分的变化;以及病死率,存活患者ICU住院天数。结果二组患者治疗前MODS严重度评分比较差异无统计学意义(P>0.05);观察组治疗后MODS评分明显下降(P<0.01),且明显低于对照组(P<0.01)。观察组比对照组病死率低(P>0.05),存活患者ICU住院天数明显缩短(P<0.05)。结论早期实施血液滤过能有效改善心肺复苏后患者的预后。
Objective To explore the therapeutic effect of early hemofiltration on patients after cardiopulmonary resuscitation. Methods A total of 42 patients with successful cardiopulmonary resuscitation were randomly divided into two groups. The control group received circulation therapy, respiratory support, brain protection and infection control. In the observation group, 24 patients were treated with hemofiltration (CVVH) for 12 hours after cardiopulmonary resuscitation (CPR) started within 4 hours after successful CPR, and observed the changes of severity scores of multiple organ dysfunction syndrome (MODS) in two groups; and the mortality, ICU stay in surviving patients . Results There was no significant difference in the severity of MODS between the two groups before treatment (P> 0.05). The MODS score of the observation group decreased significantly (P <0.01) and was significantly lower than that of the control group (P <0.01). The death rate in observation group was lower than that in control group (P> 0.05), and the length of hospital stay in ICU was significantly shorter in survivors (P <0.05). Conclusion The early implementation of hemofiltration can effectively improve the prognosis of patients after cardiopulmonary resuscitation.