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在治疗中甲氰咪胍常与其他药物合并应用,但在合并用药中不良反应需引起警惕。现将与甲氰咪胍合用的药物及其毒副反应分述如下: 1.与氨茶碱合用:使体内排茶碱的能力降低60%,引起积蓄中毒,据国外报导由茶碱引起的惊厥而致死亡者有半数以上。 2.与吗啡合用:可致呼吸骤停,因抑制了吗啡的排出率,使呼吸抑制严重缺氧,并出现传导阻滞。 3.与利多卡因合用:冠心病人用甲氰咪胍是为清除上消化道症状,但合并用药中
Cimetidine in the treatment of often combined with other drugs, but adverse reactions in the combined medication need to be vigilant. Drugs and cimetidine will now be combined with the drug side effects are described below: 1. And aminophylline combination: the body’s ability to reduce theophylline 60%, causing accumulation of poisoning, according to foreign reports were caused by theophylline Convulsions caused more than half of those who died. 2. And morphine combined: can cause respiratory arrest, due to the inhibition of morphine’s rate of discharge, so that respiratory depression, severe hypoxia, and block. 3. Combined with lidocaine: Cimetidine in patients with coronary heart disease is to clear the upper gastrointestinal symptoms, but the combination of medication