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作者对20例肺癌、21例大肠癌患者做了白细胞对抗癌药物敏感性实验,同时以癌细胞药敏实验作对照。发现肺癌病人癌细胞对VP16、VDS、VCR、PYM、5-Fu、IFO、CTX等药物的敏感性低于白细胞药敏,其中对CTX药敏性差异显著(P<0.05)。大肠癌患者癌细胞对八种抗癌药物敏感性高于白细胞,其中对5-Fu、MMC、CTX、DDP有非常显著的差异(P<0.05~0.01)。发现白细胞对抗癌药物敏感性有肿瘤、个体和药物差异性。
The author of the 20 cases of lung cancer, 21 cases of colorectal cancer patients with leukocyte anti-cancer drug sensitivity test, while the susceptibility test of cancer cells as a control. The sensitivity of cancer cells to VP16, VDS, VCR, PYM, 5-Fu, IFO, CTX and other drugs was lower than that of leukocyte sensitization, and the sensitivity to CTX was significantly different (P<0.05). The sensitivity of colorectal cancer patients to eight anti-cancer drugs was higher than that of leukocytes. There was a significant difference between 5-Fu, MMC, CTX, and DDP (P<0.05-0.01). It has been found that the sensitivity of white blood cells to anti-cancer drugs is tumor, individual and drug differences.