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作者对56例窒息新生儿和15例正常新生儿进行了心肌酶谱的动态观察。结果重度窒息组AST、CPK、CPD-MB、LDH、α-羟丁酸及LDH_1均明显高于轻度窒息组(P<0.02)及对照组(P<0.01),窒息组治疗前后(生后24小时内及生后5～7天)对比呈下降趋势,治疗后明显低于治疗前(P<0.02),指出窒息时心肌酶谱特别是CPK-MB的改变在心肌损害的判断上有重要意义,并有助于早期预测心功能的损害以便及时治疗,以免进一步发展为心衰及心源性休克。
The author of 56 cases of asphyxia neonates and 15 cases of normal newborn myocardial dynamic changes of myocardial enzymes. Results The levels of AST, CPK, CPD-MB, LDH, α-hydroxybutyric acid and LDH 1 in severe asphyxia group were significantly higher than those in mild asphyxia group and control group (P <0.01) 24 hours and 5-7 days after birth) showed a downward trend, after treatment was significantly lower than before treatment (P <0.02), pointed out that asphyxia myocardial enzymes, especially CPK-MB changes in the judgment of myocardial damage is important Meaning, and help early prediction of cardiac function damage for timely treatment, so as to avoid further development of heart failure and cardiogenic shock.