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目的:探讨不同性别的老年单纯性收缩期高血压(ISH)患者肥胖指标及高敏C反应蛋白(hs-CRP)水平有无差异。方法:选择ISH老年患者144例,测定患者身高、体重、体质指数、腰围、臀围及腰臀比(WHR),测定外周空腹静脉血hs-CRP。结果:男女ISH患者超重及肥胖比例无显著性差异。女性WC≥80cm或WHR≥0.85分别占65.28%及61.11%;男性WC≥85cm或WHR≥0.90分别为48.61%及44.44%,女性腹型肥胖比例明显高于男性,P<0.05。女性hs-CRP水平明显高于男性,回归分析显示仅女性的腰围是hs-CRP的影响因素。结论:炎症反应可能通过腹型肥胖参与女性ISH的发病过程。
Objective: To investigate the differences of obesity index and high-sensitivity C-reactive protein (hs-CRP) levels in elderly patients with isolated systolic hypertension (ISH) of different genders. Methods: The age, weight, body mass index, waist circumference, hip circumference and waist-to-hip ratio (WHR) were measured in 144 elderly patients with ISH and hs-CRP in peripheral blood was measured. Results: There was no significant difference in overweight and obesity among men and women with ISH. Women WC≥80cm or WHR≥0.85 accounted for 65.28% and 61.11% respectively; men WC≥85cm or WHR≥0.90 were 48.61% and 44.44% respectively. The percentage of abdominal obesity in women was significantly higher than that in men (P <0.05). Female hs-CRP levels were significantly higher than men, regression analysis showed that only women’s waist circumference is hs-CRP factors. Conclusion: Inflammatory reaction may be involved in the pathogenesis of female ISH through abdominal obesity.