丙戊酸钠(DPA)虽已合成约一世纪,但仍是一种新的抗癫痫药.此药有广谱抗痉活力,对全身性发作比部分性发作更有效.药理的研究表明,DPA对自主神经系无影响,对心血官、肾脏或呼吸亦无明显作用.成人每日剂量一般为900～1500mg,治疗的血浓度约50～100μg/ml.DPA的付作用甚少,文献中最常见的是胃肠道 Although sodium valproate (DPA) has been synthesized for about a century, it is still a new antiepileptic drug which has broad-spectrum antispasmodic activity and is more effective than generalized seizures on systemic attacks.Physical studies have shown that, DPA has no effect on the autonomic nervous system, nor does it exert a significant effect on cardiovascular organs, kidneys, or respiration. The daily dosage for adults is usually 900-1500 mg and the blood concentration for treatment is about 50-100 μg / ml. The most common is the gastrointestinal tract