论文部分内容阅读
[目的]观察化湿活血汤联合西药治疗2型糖尿病下肢周围神经病变疗效。[方法]使用随机平行对照方法,将156例住院患者按掷骰子法简单随机分为两组。对照组78例降血糖;甲钴胺,0.5mg/次,1次/d。治疗组78例化湿活血汤(薏苡仁30g,黄芪24g,丹参20g,葛根、地龙、川牛膝、木瓜、赤芍、白芍各15g,黄柏、黄芩各10g,川芎、苍术各9g,桂枝6g,黄连5g,水蛭、甘草各3g),1剂/d,水煎400m L,早晚口服,200m L/次;西药治疗同对照组。连续治疗60d为1疗程。观测临床症状、全血黏度、血浆黏度、总胆固醇、三酰甘油、NIHSS评分、MDNS评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效44例,有效24例,无效10例,总有效率87.18%。对照组显效30例,有效23例,无效25例,总有效率67.95%。治疗组疗效优于对照组(P<0.01)。评分指标两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。血液指标两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]化湿活血汤联合西药治疗2型糖尿病下肢周围神经病变疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Huashi Huoxue Decoction combined with western medicine on peripheral neuropathy of lower extremity in type 2 diabetes mellitus. [Methods] Using randomized parallel control method, 156 inpatients were randomly divided into two groups according to the method of dice rolling. The control group, 78 cases of hypoglycemia; mecobalamin, 0.5mg / time, 1 / d. 78 cases of Huashi Huoxue Decoction (Yiyiren 30g, Astragalus 24g, Salvia 20g, Pueraria lobata, Radix Achyranthes, papaya, red peony root, white peony root each 15g, Treats, Scutellaria the 10g, Chuanxiong, herb each 9g, Guizhi 6g, Coptis 5g, leeches, licorice 3g), 1 / d, decoction 400m L, morning and evening oral, 200m L / times; Western medicine treatment with the control group. Continuous treatment of 60d for a course of treatment. Clinical symptoms, whole blood viscosity, plasma viscosity, total cholesterol, triglyceride, NIHSS score, MDNS score and adverse reactions were observed. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group was effective in 44 cases, effective in 24 cases, ineffective in 10 cases, the total effective rate was 87.18%. The control group, markedly effective in 30 cases, effective in 23 cases, ineffective in 25 cases, the total effective rate was 67.95%. The treatment group than the control group (P <0.01). Scoring index improved in both groups (P <0.01), the treatment group improved better than the control group (P <0.01). Blood index improved in both groups (P <0.01), and the treatment group improved better than the control group (P <0.01). [Conclusion] Huashi Huoxue Decoction combined with Western medicine in the treatment of peripheral neuropathy of type 2 diabetes mellitus has satisfactory curative effect and no serious adverse reactions, which is worthy of popularization.