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合并用药的根本目的在于提高疗效,消除或减少毒副反应。随着临床药学和临床药理的迅速发展,开展治疗药物监测发现:并用药物越多,药物相互作用的发生率就越高。近年来医药科学技术日新月异,涌现出很多新药,新药和老药并用以及新药和新药、老药和老药并用后相互作用以及应用到人体内的变化,是一个错综复杂的问题。因此,如何才能做到合理用药,既提高疗效,又确保安全,就成为临床医师和药师面临的日益突出的问题。根据本人搜集到的有关资料,结合临床典型病例,合并用药对疗效的影响主要表现在:
The fundamental purpose of the combination of medication is to improve the efficacy, eliminate or reduce side effects. With the rapid development of clinical pharmacy and clinical pharmacology, the monitoring of therapeutic drugs found that the more concurrent drugs, the higher the incidence of drug interactions. In recent years, with the ever-changing medical science and technology, the emergence of many new drugs, new drugs and old drugs used in combination with new drugs and new drugs, old drugs and old drugs after the interaction and application to the human body changes, is a complicated problem. Therefore, how to make rational use of drugs not only improves curative effect, but also ensures safety, has become an increasingly prominent problem for clinicians and pharmacists. According to the information I collected, combined with the typical clinical cases, the impact of the combination of drugs on the efficacy mainly in: