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长期应用肾上腺皮质激素(简称激素)诱发的结核病,称为类固醇性结核病。本院1990～1997年住院的类固醇性结核病12例,通过回顾性分析,旨在提醒临床工作者注意,激素对结核病的双重作用,并就类固醇性结核病的预防及治疗进行分析探讨。1 临床资料1.1 病例选择 1990～1997年在应用类固醇激素过程中出现结核病12例。男8例,女4例,年龄18～66岁,平均40.2岁。其中5例为原有结核病史,已正规化疗结束,因应用激素复发;另7例为自身免疫性疾病患者。以上病例均经痰细菌学,X线以及病理学证实。其中血行播散型肺结核(Ⅱ型)6例,继发型肺结核(Ⅲ型)4例,结核性胸膜炎(Ⅳ型)2例。
Long-term use of adrenal cortex hormones (referred to as hormone) induced tuberculosis, known as steroid tuberculosis. Our hospital from 1990 to 1997 steroid-resistant tuberculosis in 12 cases, through a retrospective analysis, to remind clinicians of attention, the dual role of hormones on tuberculosis, and steroid-resistant tuberculosis prevention and treatment analysis. 1 Clinical data 1.1 Case Selection 1990 to 1997 in the application of steroid hormones occurred in 12 cases of tuberculosis. 8 males and 4 females, aged 18 to 66 years, an average of 40.2 years old. Among them, 5 cases had the history of the original tuberculosis, and the formal chemotherapy was completed because of hormone recurrence. The other 7 cases were patients with autoimmune diseases. The above cases were sputum bacteriology, X-ray and pathology confirmed. Among them, 6 were hematogenous disseminated pulmonary tuberculosis (type Ⅱ), 4 were secondary tuberculosis (type Ⅲ) and 2 were tuberculous pleurisy (type Ⅳ).