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目的探讨血尿酸水平与冠状动脉粥样硬化性心脏病(冠心病)的关系及临床意义。方法检测经冠状动脉造影确诊的冠心病患者70例与40例非冠心病患者的血尿酸水平,并将冠心病按稳定型心绞痛(A组)、不稳定型心绞痛(B组)、急性心肌梗死(C组)分为三组,并进行相关的统计学分析。结果与对照组比较,冠心病组患者血尿酸水平明显高于对照组(P<0.05),冠心病组中B组与A组,C组与A组比较差异有统计学意义(P<0.05),而B组与C组比较差异无统计学意义。结论高尿酸血症是冠心病发病的一个相关因素。
Objective To investigate the relationship between serum uric acid level and coronary atherosclerotic heart disease (CHD) and its clinical significance. Methods Serum uric acid levels in 70 patients with coronary heart disease and 40 patients with non-coronary heart disease confirmed by coronary angiography were measured. The patients with stable angina (group A), unstable angina (group B), acute myocardial infarction (Group C) were divided into three groups, and related statistical analysis. Results Compared with the control group, the level of serum uric acid in CHD group was significantly higher than that in control group (P <0.05). There was significant difference between group B and group A, C and group A (P <0.05) , While there was no significant difference between group B and group C Conclusion Hyperuricemia is a related factor in the pathogenesis of coronary heart disease.