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目的:探讨慢性失眠症患者饮酒后首次服用氯氮平出现意识障碍的相关因素及临床特点。方法:对近6年经本院急诊室抢救治的18例失眠患者进行回顾性分析。结果:其中安眠类药物合并酒精成瘾2例(占11.1%),安眠类药物成瘾6例(33.3%),神经衰弱10例(55.6%)。结论:意识障碍的发生与饮酒后服用氯氮平有直接因果关系。
Objective: To explore the related factors and clinical features of consciousness disorder in patients with chronic insomnia who take clozapine for the first time after drinking alcohol. Methods: 18 cases of insomnia treated by emergency department in our hospital in recent 6 years were retrospectively analyzed. Results: There were 2 cases (11.1%) of hypnotic drugs combined with alcohol addiction, 6 cases (33.3%) of hypnotic drugs addiction and 10 cases of neurasthenia (55.6%). Conclusion: The incidence of disturbance of consciousness has direct causal relationship with taking clozapine after drinking alcohol.