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目的 评价青蒿琥酯预防血吸虫病的效果。方法 对 1998年参加长江九江段及鄱阳湖区抗洪抢险接触疫水的 3 2 6 4名武警官兵给予口服青蒿琥酯 ,并调查血吸虫病感染情况。结果 3 2 6 4名武警官兵中无急性血吸虫病发生 ,脱离疫水后 1个月检查 ,总粪检阳性率为 0 0 3 % ,血检阳性率为 1 5 % ;其中参加长江九江段抗洪抢险的武警官兵服用青蒿琥酯完全者没有发现血吸虫病阳性者 ,参加鄱阳湖区抗洪抢险的阳性率为 1 6 3 % ,均低于同期同地未服药组的阳性率 (P >0 0 5 )。结论 提示青蒿琥酯对短期突击下水人群预防血吸虫病有良好的效果
Objective To evaluate the efficacy of artesunate in the prevention of schistosomiasis. Methods A total of 3 264 armed police officers and men participating in flood fighting and emergency contact with water in the Jiujiang Section of the Yangtze River and Poyang Lake in 1998 were given artesunate orally and the infection of schistosomiasis was investigated. Results There were no acute schistosomiasis among 3 2 6 4 armed police officers and 1 month after the water was expelled. The positive rate of total fecal examination was 0 0 3% and the positive rate of blood test was 15%. Among them, Rescue armed police officers and men taking artesunate completely did not find schistosomiasis positive persons to participate in the Poyang Lake area flood fighting and rescue the positive rate was 163%, were lower than the same period in the same place without the group the positive rate (P> 0 0 5 ). Conclusions suggest that artesunate has a good effect on the prevention of schistosomiasis in short-term surprise launching