目的:应用妈富隆配伍四物汤配方颗粒治疗围绝经期功能失调性子宫出血,并阐明其作用机理。方法:90例围绝经期功血患者应用复方口服避孕药妈富隆配合四物汤配方颗粒纠正贫血症状。结果:中西医结合组90例治愈83例,好转7例,与妈富隆组比较差异有统计学意义(P<0.05)。结论:妈富隆配合中药治疗围绝经期功血安全有效、费用低廉。 Objective: To apply MaFuLong and SiWu Tang formula granule in the treatment of dysfunctional uterine bleeding in perimenopausal period and elucidate its mechanism. Methods: 90 cases of climacteric dysfunctional uterine bleeding patients with compound oral contraceptives Marvelon with Siwutang formula particles to correct the symptoms of anemia. Results: In the 90 cases of traditional Chinese and western medicine group, 83 cases were cured and 7 cases improved. There was a significant difference between them (P <0.05). Conclusion: Marvelon combined with traditional Chinese medicine is safe and effective in perimenopausal dysfunctional uterine bleeding and has low cost.