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目的观察慢性化脓性中耳炎患者中耳脓性分泌物的病原菌分布情况及其药物敏感性,以指导临床用药。方法对123例慢性化脓性中耳炎患者123耳的中耳脓性分泌物进行细菌培养,并对分离的病原菌进行药物敏感试验。结果123耳标本中分离培养出病原菌103耳,其中细菌99耳,真菌4耳;无细菌生长20耳。以金黄色葡萄球菌(21耳)和铜绿假单胞菌(19耳)为主,其次为表皮葡萄球菌(13耳)和肺炎克雷伯杆菌(10耳)等。不同的细菌有各自的敏感药物谱。结论金黄色葡萄球菌和铜绿假单胞菌是慢性化脓性中耳炎的主要致病菌,抗菌药物敏感试验对临床用药有指导意义。
Objective To observe the distribution of pathogenic bacteria of middle ear purulent secretions in patients with chronic suppurative otitis media and its drug sensitivity to guide the clinical medication. Methods 123 cases of middle ear purulent secretions from patients with chronic suppurative otitis media were cultured in vitro and drug susceptibility tests were carried out on the isolated pathogens. Results 123 ear pathogen isolated and cultured 103 ears, of which 99 bacteria, fungi 4 ears; no bacterial growth of 20 ears. Staphylococcus aureus (21 ears) and Pseudomonas aeruginosa (19 ears) were the main species, followed by Staphylococcus epidermidis (13 ears) and Klebsiella pneumoniae (10 ears). Different bacteria have their own sensitive drug spectrum. Conclusion Staphylococcus aureus and Pseudomonas aeruginosa are the main pathogens of chronic suppurative otitis media. The antimicrobial susceptibility test is instructive for clinical use.