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研究肠内营养对艾滋病患者肠道生物屏障的影响,收集艾滋病患者粪便标本30份,应用实时荧光定量PCR法检测不同细菌的数量,肠内营养服用前与服用后4周细菌数量:乳酸杆菌属(4.89±1.23,7.85±1.12)、双歧杆菌属(5.68±1.35,8.26±1.28),服用后细菌数量明显升高(P<0.05),拟杆菌属(7.65±0.48,5.22±0.34)、梭杆菌属(7.69±0.65,5.32±0.53)、梭菌属(6.12±0.25,4.32±0.28).服用后细菌数量明显降低(P<0.05);艾滋病患者存在肠道菌群失调,肠内营养能改善艾滋病患者肠道微生态.
To study the effect of enteral nutrition on the intestinal bio-barrier in AIDS patients, 30 samples of AIDS patients were collected, and the numbers of different bacteria were detected by real-time fluorescence quantitative PCR. The numbers of bacteria before and 4 weeks after enteral nutrition were: (4.89 ± 1.23, 7.85 ± 1.12) and Bifidobacterium (5.68 ± 1.35, 8.26 ± 1.28) respectively. The number of bacteria was significantly increased after treatment (P <0.05) Clostridium (7.69 ± 0.65,5.32 ± 0.53), Clostridium (6.12 ± 0.25,4.32 ± 0.28) .After taking the number of bacteria was significantly reduced (P <0.05); AIDS patients with intestinal flora, enteral nutrition Can improve gut microbiota in AIDS patients.