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目的:分析连续性肾脏替代疗法(CRRT)治疗重度颅脑损伤对颅内压的影响。方法:18例重度颅脑损伤伴高颅内压患者,给予CRRT治疗,有创颅内压监护仪全程监护颅内压,监测血清钠浓度及尿素氮(BUN)及肌酐(Scr)水平并监测患者的生命体征。结果:CRRT组颅内压较常规治疗组显著下降(P<0.05),离子紊乱率明显减少(P<0.05),生存率较对照组率有明显提高。结论:CRRT可安全有效纠正重度颅脑损伤病人高颅内压,高钠血症,有效降低死亡率。
Objective: To analyze the effect of continuous renal replacement therapy (CRRT) on intracranial pressure in patients with severe craniocerebral injury. Methods: Eighteen patients with severe traumatic brain injury and severe intracranial pressure were treated with CRRT. The intracranial pressure was monitored by intracranial pressure monitor. The levels of serum sodium, urea nitrogen (BUN) and creatinine (Scr) were monitored and monitored The patient’s vital signs. Results: The intracranial pressure in CRRT group was significantly lower than that in conventional treatment group (P <0.05), the ion disorder rate was significantly decreased (P <0.05), and the survival rate was significantly higher than that in control group. Conclusion: CRRT can safely and effectively correct high intracranial pressure and hypernatremia in patients with severe craniocerebral injury and effectively reduce the mortality rate.