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胰腺癌的早期诊断率和切除率至今不能令人满意。Korprowski等发现一种单克隆抗体,能与胃肠道腺癌患者血清中的抗原(GICA)起反应,这一抗原在正常人血清中浓度很低,但对胰腺癌病人特别有意义。本研究旨在评价此抗原作为胰腺癌标记的敏感性和特异性。材料与方法:正常人29名(男15人,女14人),胰腺疾病患者59例,计有急性胰腺炎10例,慢性胰腺炎27例,胰腺癌22例。用固相放射免疫技术测定
The early diagnosis rate and resection rate of pancreatic cancer have not been satisfactory so far. Korprowski et al. discovered a monoclonal antibody that reacts with the antigen in the serum of patients with gastrointestinal adenocarcinoma (GICA). The concentration of this antigen in normal human serum is very low, but it is particularly significant for patients with pancreatic cancer. This study aimed to evaluate the sensitivity and specificity of this antigen as a pancreatic cancer marker. Materials and Methods: 29 normal subjects (15 males and 14 females) and 59 patients with pancreatic diseases, including 10 cases of acute pancreatitis, 27 cases of chronic pancreatitis, and 22 cases of pancreatic cancer. Determined by solid-phase radioimmunoassay