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目的探讨胱抑素C(Cys C)与尿微量白蛋白(U-m Alb)联合检测对高血压肾病患者的诊断价值。方法选择2015年5月至2016年5月收治的60例高血压无肾病患者和60例高血压肾病患者,分别检测其Cys C和U-m Alb,并与对照组(健康受检者)的Cys C和U-m Alb水平进行比较分析。结果高血压肾病组U-m Alb、Cys C的浓度明显高于高血压无肾病组和对照组,观察U-m Alb、Cys C的阳性率发现,对照组、高血压无肾病组、高血压肾病组逐渐升高,差异有统计学意义(P<0.05)。结论对高血压肾病患者检测Cys C与U-m Alb的临床价值较高,其是早期诊断肾脏损伤的敏感指标,能辅助临床早期进行干预和治疗,值得大力推广使用。
Objective To investigate the diagnostic value of cystatin C (Cys C) combined with urinary microalbumin (U-m Alb) in patients with hypertensive nephropathy. Methods Sixty patients with hypertensive nephropathy and 60 patients with hypertensive nephropathy were recruited from May 2015 to May 2016. Their Cys C and Um Alb were detected respectively and compared with those of control subjects (healthy subjects) And Um Alb level for comparative analysis. Results The levels of Um Alb and Cys C in hypertensive nephropathy group were significantly higher than those in non-hypertensive nephropathy group and control group. The positive rates of Um Alb and Cys C were found in control group, hypertensive nephropathy group and hypertensive nephropathy group High, the difference was statistically significant (P <0.05). Conclusions The detection of Cys C and U-m Alb in patients with hypertensive nephropathy is of high clinical value. It is a sensitive indicator of early diagnosis of renal injury. It may be helpful to early intervention and treatment in clinical practice and should be widely promoted.