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全氟辛烷磺酸作为一种新型持久性有机污染物,其对全球生态所造成的严重污染现象已受到社会越来越多的关注。本文介绍了全氟辛烷磺酸对精子发育成熟、血睾屏障结构与功能、睾酮合成的影响以及经此途径诱导雄性生殖损伤相关机制,综述全氟辛烷磺酸对雄性动物生殖毒性的研究进展。
As a new type of persistent organic pollutant, perfluorooctane sulfonate has drawn more and more attention from the society due to its serious pollution caused by the global ecology. This paper describes the effects of PFOS on the maturation of sperm, the structure and function of the blood-testis barrier, the synthesis of testosterone and the mechanism of male reproductive injury induced by this pathway. The reproductive toxicity of PFOS to male animals is reviewed progress.