老年人眼底的脉络膜常有新生血管发生,这种新生血管穿过有病变的玻璃膜侵入视网膜,在色素上皮下蔓延。当色素上皮发生病变时,又可侵及视网膜下间隙,形成很薄的一层血管膜。大多数的新生血管膜很少引起患者的主觉症状。少数浸润性的新生血管膜有渗漏。渗漏出的浆液和血液常聚积在组织间隙中,引起视网膜水肿和色素上皮脱离,或知觉上皮脱离,并有纤维组织增生。病变的形态多呈盘状,因此人们称之为盘状反应(disciform response)。病变发生在黄斑部,中心视力受到严重损害,是目前较发达国家老年人致盲的主要原因。脉络膜新生血管膜也见于高度近视眼、视网膜血管样条纹、多灶性内层(似组织胞浆菌病)脉络膜炎、以及长期视网膜色素 The choroid in the eyes of the elderly often have neovascularization, which penetrates the diseased glass membrane into the retina and spreads under the pigment epithelium. When lesions occur when the pigment epithelium, but also invasion of the subretinal space, the formation of a thin layer of vascular membrane. Most neovascular membranes rarely cause the patient’s symptoms. A small number of invasive neovascular membrane leakage. Leakage of serum and blood often accumulate in the interstitial tissue, causing retinal edema and pigment epithelial detachment, or sensory epithelial detachment, and fibrous tissue hyperplasia. The morphology of the lesions is mostly disk-shaped, so people call it a disciform response. Lesions occur in the macula, central vision was severely damaged, is the main reason for blindness in the elderly in the more developed countries. Choroidal neovascularization is also seen in high myopia, retinal vascular stripe, multifocal inner layer (like histoplasmosis) choroiditis, and long-term retinal pigment