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心肌缺血再灌注损伤指的是心肌短时间血供中断后,一定时间内再次恢复心肌血液供应,缺血心肌发生较血液供应恢复前更严重的损伤。二十世纪八十年代,有学者提出缺血预适应概念,是指多次短暂缺血对随后较长时间心肌缺血再灌注损伤产生保护的一种适应机制。缺血预处理是保护心肌细胞,减轻心肌再灌注损伤的有效方法,成了医学领域的热门研究课题之一。但由于临床心肌细胞缺血事件不能够事先预见,以及实施缺血预适应过程对心脏
Myocardial ischemia-reperfusion injury refers to a short period of myocardial blood supply interruption, again within a certain period of time to restore myocardial blood supply, ischemic myocardium occurred before the blood supply recovery more serious injury. In the 1980s, some scholars proposed the concept of ischemic preconditioning, which is an adaptive mechanism of multiple transient ischemia to protect myocardial ischemia-reperfusion injury after a long period of time. Ischemic preconditioning is an effective method to protect myocardial cells and reduce myocardial reperfusion injury, which has become one of the hot research topics in the medical field. However, due to clinical myocardial ischemia can not predict in advance, and the implementation of ischemic preconditioning process on the heart