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目的:总结他达拉非治疗西地那非治疗无效的勃起功能障碍患者的诊疗经验。方法:回顾总结2010年9月至2012年3月15例按需口服西地那非治疗无效的勃起功能障碍患者的病例资料。结果:15例按需口服西地那非治疗无效的勃起功能障碍患者中,11例治疗后勃起功能改善明显,4例改善不明显,有效率73.3%。治疗前后IIEF-5评分比较有显著性差异(P<0.05),疗效满意。4例患者出现不良反应,其中轻微头痛2例,颜面潮红1例,1例出现轻微的腰背痛,均为一过性,继续用药后减轻或消失。结论:按时口服他达拉非是治疗按需口服西地那非治疗无效的勃起功能障碍患者的安全有效方法。
OBJECTIVE: To summarize the diagnosis and treatment experience of tadalafil in the treatment of idiopathic erectile dysfunction in sildenafil patients. Methods: The data of 15 patients with erectile dysfunction on demand oral sildenafil from September 2010 to March 2012 were retrospectively summarized. Results: Of the 15 patients with erectile dysfunction who were on-demand oral sildenafil treatment, erectile dysfunction was significantly improved in 11 patients with no significant improvement in 4 patients, with an effective rate of 73.3%. Before and after treatment IIEF-5 scores were significantly different (P <0.05), with satisfactory results. Four patients had adverse reactions, including 2 mild headache, 1 flushing and 1 slight back pain. All of them were transient and continued to decrease or disappear after treatment. Conclusion: Oral administration of tadalafil on time is a safe and effective method for the treatment of patients with erectile dysfunction who require oral sildenafil on-demand.