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目的 探讨外科治疗肺原发性混合癌的手术疗效。方法 回顾性分析了 20年内 19例肺混合癌手术治疗情况及预后,其占同期肺癌手术的 5.23%。 19例中Ⅱ b期 4例,Ⅲ a期 8例,Ⅲ b期 5例,Ⅳ期 2例。结果 3年生存率为 21.05%, 5年生存率为 15.79%。结论 肺原发性混合癌有其独特的生物学性质,预后较差,生存率较低,接近或稍高于小细胞肺癌。Ⅱ期病例主张积极手术治疗,争取早期诊断,早期治疗,以期获得满意疗效。Ⅲ期病例手术应慎重考虑,宜采取以手术治疗为主,术后辅助放疗、化疗,以延长存活期。
Objective To investigate the surgical treatment of primary mixed lung cancer surgery. Methods Retrospective analysis of 19 cases of lung cancer surgery and prognosis in 20 years, which accounted for 5.23% of lung cancer surgery over the same period. Among the 19 cases, there were 4 cases of stage Ⅱ b, 8 cases of stage Ⅲ a, 5 cases of stage Ⅲ b and 2 cases of stage Ⅳ. Results The 3-year survival rate was 21.05% and the 5-year survival rate was 15.79%. Conclusions Pulmonary primary mixed carcinoma has its unique biological properties with poor prognosis and lower survival rate, which is close to or slightly higher than that of small cell lung cancer. Phase Ⅱ cases advocate active surgical treatment, for early diagnosis and early treatment, in order to obtain satisfactory results. Ⅲ cases of surgery should be carefully considered, it is appropriate to take surgical treatment, postoperative adjuvant radiotherapy and chemotherapy to prolong survival.