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随着肝、胰移植的相继成功,小肠移植的研究亦已兴起。近年来,尽管对肠切除后残余肠段代偿性增生的机制尚未阐明,但研究发现,营养因素可能起着重要的作用。胃泌素对胃粘膜有营养作用;肠促胰酶肽对胰腺有营养作用;而表皮生长因子如同尿抑胃素可刺激小肠细胞增殖;肠增血糖素是肠道的生长激素,它可在小肠切除后释放并促进小肠粘膜的增生。目前尚无提纯的化学制剂作为小肠营养因子的报道,但肠切后肠粘膜增殖的刺激多数是受化学调节剂
With the success of liver and pancreas transplantation, researches on small bowel transplantation have also emerged. In recent years, although the mechanism of compensatory proliferation of the residual bowel segment after intestine resection has not been elucidated, the study found that nutritional factors may play an important role. Gastrin has a nourishing effect on the gastric mucosa; trypsin peptide has a nutritive effect on the pancreas; and epidermal growth factor like urbustatin stimulates intestinal cell proliferation; incretin is a gut growth hormone that can Small intestine resection release and promote small intestinal mucosal hyperplasia. At present there is no purification of chemicals as small intestine trophic factor reported, but after intestinal stimulation of intestinal mucosal proliferation stimuli by chemical regulators