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目的探讨男女尖锐湿疣(CA)患者心理状态,观察心理干预联合常规治疗对女性CA患者预后的影响。方法对男性和女性CA患者各110例进行焦虑自评量表(SAS)和抑郁自评量表(SDS)评定,同时将女性CA患者有负性情绪的100例,随机分为观察组和对照组,观察组给予微波加5-氨基酮戊酸-光动力(ALA-PDT)照射,光照期间同时给予心理干预,而对照组单纯给予微波和ALA-PDT,观察治疗后的复发率及SAS、SDS评分的变化。结果男性CA患者、女性CA患者、国内常模SAS和SDS评分比较,差异均有统计学意义(F=12.76,P<0.01;F=20.30,P<0.01);有负性情绪的女性CA患者,观察组较对照组CA复发率降低,差异有统计学意义(χ2=6.618,P<0.05);观察组治疗后SAS、SDS评分均降低,与治疗前比较差异均有统计学意义(t=19.16,P<0.01;t=23.09,P<0.01)。结论 CA患者存在负性情绪,尤其是女性CA患者,心理干预联合常规治疗可缓解患者焦虑、抑郁负性情绪,降低CA的复发率。
Objective To investigate the psychological status of male and female patients with condyloma acuminatum (CA) and observe the effect of psychological intervention and routine treatment on the prognosis of female patients with CA. Methods A total of 110 male and female CA patients were evaluated by self-rating anxiety scale (SAS) and depression self-rating scale (SDS). At the same time, 100 female patients with negative emotion were randomly divided into observation group and control group The mice in the observation group were treated with microwave and 5-aminolevulinic acid-photodynamic therapy (ALA-PDT). Psychological intervention was given during the light irradiation while the control group was given microwave and ALA-PDT alone. The relapse rate and SAS, Changes in SDS score. Results There was significant difference between male CA patients and female CA patients, and the scores of SAS and SDS in the national norm (F = 12.76, P <0.01; F = 20.30, P <0.01) , The recurrence rate of CA in the observation group was lower than that in the control group (χ2 = 6.618, P <0.05). The scores of SAS and SDS in the observation group decreased after treatment, which were significantly different from those before treatment (t = 19.16, P <0.01; t = 23.09, P <0.01). Conclusion There is negative emotion in CA patients, especially in female CA patients. Psychological intervention combined with routine treatment can relieve anxiety and depression, and reduce the relapse rate of CA.