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目的 探讨各年龄组男性急性心肌梗死患者的临床特点.方法 将临床确诊急性ST段抬高型心肌梗死的158例男性患者分为青年组(年龄26~44岁,37例)、中年组(年龄45~59岁,65例)和老年组(年龄60~89岁,56例),分析各组患者冠心病危险因素和冠状动脉病变特点.结果 冠心病危险因素中,青年组体质指数、甘油三酯、总胆固醇、吸烟比例显著高于老年组(P<0.05);中年组糖尿病比例显著高于青年组(P<0.05).冠状动脉造影显示青年组单支病变发生率(64.9%)明显高于中年组及老年组(P<0.05),Gensini评分轻度病变发生率(29.7%)明显高于老年组(P<0.05);老年组多支病变及左主干病变发生率明显高(P<0.05).老年组NT-ProBNP峰值显著高于青年组及中年组(P0.05).结论 体质指数高、高脂血症、吸烟是青年患者主要的危险因素,虽冠脉受累支数及病变相对轻,但心梗面积与老年患者相当.应重视冠心病患者,尤其是对青年患者进行生活方式宣教,综合干预其危险因素.“,”Objective To observe the clinical characteristics of male patients with acute myocardial infarction(AMI)in different age groups. Methods 158 cases of male patients with clinical diagnosis of acute ST elevation myocardial infarction were divided into young aged group(aged 26 to 44 years old,37 cases),middle aged group(aged 45 to 59 years old,65 cases)and elderly group(age 60 to 89 years old,56 cases).The risk factors and characteristics of coronary lesions were analyzed in each group.Results Body mass index,triglyceride,total cholesterol and proportion of smokers were significantly higher in the young aged group than that in the elderly group(P<0.05).The middle aged group had more patients with diabetes (P<0.05). The incidence of single vessel disease in the young group (64.9%) was higher than that in the middle aged group and the elderly group(P<0.05).Meanwhile,the incidence of mild lesion of Gensini integral (29.7%) was higher than that of the elderly group (P<0.05). The elderly group had higher incidence of multivessel and left main stem disease than the other groups(P<0.05).The peak value of NT-ProBNP in the elderly group was significantly higher than that in the young aged group and the middle aged group(P0.05).Conclusion High BMI, hyperlipidemia, and smoking were the main risk factors of young patients with AMI. Although young patients had relatively lighter coronary lesions,they had similar myocardial infarction size when compared to elderly patients.It is important to pay attention to coronary heart disease,especially for young patients,by carrying out a healthy lifestyle and controlling risk factors.