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目的通过肺癌术中胸腔冲洗液细胞学检测探讨其对肺癌患者3年生存率的预后价值。方法选择上海市胸科医院胸外科1998-10/2002-05收治的无恶性胸腔积液的100例肺癌患者,剖胸后及术毕胸膜腔冲洗,冲洗液行病理细胞学检查,术后患者随访。结果冲洗液细胞学:术前阳性8例,术后阳性5例。3年生存率随访:冲洗液细胞学阳性者为20%,阴性者为60%。冲洗液阳性的相关因素包括:病理分期、细胞类型、肿瘤大小、胸膜侵犯程度。结论术中胸膜腔冲洗液细胞学检查可提示胸膜腔的微转移,是一个重要的预后因素。
Objective To investigate the prognostic value of three-year survival rate of patients with lung cancer through intraoperative pleural fluid cytology. Methods One hundred patients with lung cancer who had malignant pleural effusion admitted from 1998 to 2002-05 in Shanghai Thoracic Hospital were enrolled in this study. Pathological cytology and cytology were performed after thoracotomy and operation, and postoperative patients Follow-up. Results Fluorescence cytology: preoperative positive in 8 cases, postoperative positive in 5 cases. Three-year survival rates were followed up: 20% positive for cytology in washings and 60% in negatives. Rinsing fluid positive related factors include: pathological stage, cell type, tumor size, pleural invasion. Conclusion Intrapleural pleural fluid washing cytology can prompt micro-metastasis of the pleural cavity is an important prognostic factor.