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目前,头颈肿瘤的综合治疗中,化疗正发挥着越来越重要的作用。但临床上如何更好地选择药物和制定疗效较高的化疗方案,却是一个亟待解决的问题。临床医师一般是参照文献及自己的经验选择用药,主观性和盲目性较大。笔者利用人体肿瘤小鼠肾包膜下接种法(subrenal Capsule assay,SRCA)作为抗癌药物敏感试验,并在头颈部肿瘤中进行了初步应用。现将其结果报道如下。
Currently, chemotherapy is playing an increasingly important role in the comprehensive treatment of head and neck cancers. However, clinically how to better select drugs and formulate chemotherapy regimens with higher efficacy is a problem that needs urgent solution. Clinicians generally choose drugs based on literature and their own experience, subjectivity and blindness are relatively large. The authors used the human kidney tumor subrenal capsule assay (SRCA) as an anti-cancer drug sensitivity test, and had preliminary application in head and neck cancer. The results are reported below.