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目的:运用循证医学、系统分析的方法对中医药治疗儿童哮喘的临床研究进行质量评价,分析在科研设计、实施及疗效评价等方面的现状及存在的问题。方法:选择来源于中国生物医学文献光盘数据库(CBMdisk)(1979～2007)和中国期刊全文数据库(CJFD,1994～2007)中,有关儿童哮喘的中医及中西医结合治疗性的随机对照文献作为评价对象。按照临床流行病学/方法学的原则和方法,制定《儿童哮喘中医药治疗性文献质量评价及信息采集表》,计算出各种情况的百分比,并评价其质量。结果:经过统计分析的结果,中医药治疗儿童哮喘确有一定的疗效,但对方法学的应用不够重视,现有的研究结论未能十分令人信服,还有待于严谨设计的大样本、多中心、随机、对照临床实验对中医药治疗儿童哮喘的疗效加以证实。结论:系统评价儿童哮喘对临床治疗决策提供较科学的依据。
OBJECTIVE: To evaluate the quality of clinical research on traditional Chinese medicine (TCM) for the treatment of asthma in children by means of evidence-based medicine and systematic analysis, and to analyze the status quo and existing problems in research design, implementation and evaluation of curative effects. Methods: Randomized controlled literature on the treatment of childhood asthma combined with traditional Chinese medicine and western medicine in CBMdisk (1979-2007) and Chinese Journal Full-text Database (CJFD, 1994-2007) was selected for evaluation Object According to the principles and methods of clinical epidemiology / methodology, formulate the “Quality Evaluation and Information Collection Table of TCM Pediatric Asthma”, calculate the percentage of each situation and evaluate its quality. Results: After statistical analysis, Chinese medicine treatment of children with asthma does have a certain effect, but the application of methodology is not enough attention, the findings of the current research has not been very convincing, yet to be carefully designed large sample, multi-center , Randomized, controlled clinical trials of Chinese medicine treatment of children with asthma to be confirmed. Conclusion: The systematic evaluation of childhood asthma provides a more scientific basis for clinical treatment decisions.