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目的调查乌鲁木齐地区男性自愿无偿献血者ALT异常与肥胖的关系。方法将血液筛查仅单纯ALT异常(乳酸脱氢酶紫外动力学法检测ALT>40 U/L)的街头男性自愿无偿献血者,根据体重指数(BMI)大小,以28为界,分为肥胖(BMI≥28)组(n=389)和正常(BMI<28)组(n=3 847);采用χ2检验分析比较2组的ALT异常率。结果ALT>40 U/L者,BMI≥28组有75人(19.30%)、BMI<28组有141人(3.66%);2组ALT异常率比较,差异具有统计学意义(χ2=178.0,P<0.01)。结论乌鲁木齐地区男性肥胖献血者ALT异常率远高于男性正常献血者;对男性肥胖献血者献血前做ALT筛查可减少血源的浪费。
Objective To investigate the relationship between abnormal ALT and obesity among men in voluntary volunteer blood donation in Urumqi. Methods Blood samples were collected from voluntary male volunteers on the street only with ALT abnormality (ALT> 40 U / L by lactate dehydrogenase ultraviolet kinetics method). According to the body mass index (BMI) (BMI≥28) group (n = 389) and normal (BMI <28) group (n = 3 847) .χ2 test was used to analyze the ALT abnormalities in the two groups. Results There were 75 persons (19.30%) in BMI≥28 group and 141 (3.66%) in BMI <28 group with ALT> 40 U / L. There was significant difference in ALT abnormalities between two groups (χ2 = 178.0, P <0.01). Conclusion The ALT abnormalities in male obesity donors in Urumqi are much higher than those in male donors. ALT screening before blood donation in male obese donors can reduce the blood waste.