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细胞动力学的研究对于探索肿瘤的发展和指导肿瘤的化疗具有特殊重要的意义。初期的研究工作多在实验动物或体外培养的肿瘤细胞中进行,这对逐步阐明细胞动力学的普遍规律作出了很大的贡献,但还不能测知个别病人的特定细胞动力学变化。近十年来,开始在急性白血病病人中应用了简易的体外标记方法,这类工作至今在国际上开展还不多,在国内尚未见报导,但所得结果证明它对于预测预后和制订切合于病人特定的细胞动力学变化的化疗方案,可以作出最直接的指导。为此,我们在这方面作了探索,现将结果报导如下。
The study of cell kinetics is of special significance for exploring the development of tumors and guiding the chemotherapy of tumors. The initial research work in experimental animals or in vitro cultured tumor cells, which progressively clarify the general laws of cell dynamics has made a significant contribution, but not yet measured specific individual patient kinetic changes. In the recent ten years, simple in vitro labeling methods have been used in patients with acute leukemia. So far there are not many reports on this kind of work in the world and no results have been reported in China. However, the obtained results prove that it is very useful for predicting the prognosis and formulating patient-specific The cytokine changes in chemotherapy regimens can make the most direct guidance. To this end, we have explored this issue and the results are reported below.