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目的了解南昌市使用的麻疹风疹联合减毒活疫苗(MR)的预防接种安全性。方法分析南昌市2012~2015年通过全国疑似预防接种异常反应(AEFI)信息管理系统收集到的与接种MR有关的AEFI数据。结果南昌市2012~2015年共报告MR AEFI病例150例,报告发生率为52.88/10万剂,其中一般反应89例,报告发生率为31.37/10万剂,以发热、红肿、硬结为主;异常反应56例,报告发生率为19.74/10万剂,均为过敏性皮疹。AEFI多发生接种后≤1d。结论南昌市使用的MR不良反应报告发生率在预期发生范围内,具有较好的安全性。
Objective To understand the vaccination safety of measles rubella combined live attenuated vaccine (MR) used in Nanchang. Methods AEFI data related to MR vaccination collected from Nanchang in 2012 ~ 2015 through the National AEFI Information Management System were analyzed. Results A total of 150 cases of MR AEFI were reported in Nanchang from 2012 to 2015, with a reported incidence of 52.88 / 100 000, of which 89 were general reactions, with a reported incidence of 31.37 / 100 000 with fever, redness and induration. Abnormal reaction in 56 cases, the reported incidence of 19.74 / 10 million doses, are allergic rash. AEFI more than 1d after inoculation. Conclusion The incidence of MR adverse reactions reported in Nanchang is within the expected range and has good safety.